Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer’s disease pathogenesis
Charlene SUPNET & Ilya BEZPROZVANNY Department of Physiology;University of Texas Southwestern Medical Center at Dallas;Dallas TX 75390-9040;USA

..............page:744-751

Physiological roles of NAADP-mediated Ca~(2+) signaling
Antony GALIONE;John PARRINGTON & Tim FUNNELL Department of Pharmacology;University of Oxford;Oxford OX1 3QT;UK

..............page:725-732

Actin,more than just a housekeeping protein at the scene of fertilization
Luigia SANTELLA & Jong T.CHUN Stazione Zoologica Anton Dohrn;Napoli 80121;Italy

..............page:733-743

Cyclic ADP-ribose and NAADP:fraternal twin messengers for calcium signaling
Hon Cheung LEE Department of Physiology;University of Hong Kong;Hong Kong;China

..............page:699-711

Early calcium dysregulation in Alzheimer’s disease:setting the stage for synaptic dysfunction
Shreaya CHAKROBORTY & Grace E.STUTZMANN Department of Neuroscience;Rosalind Franklin University/the Chicago Medical School;North Chicago IL 60064;USA

..............page:752-762

Building the DREAM interactome
Marcos RIVAS 1;2;Diego VILLAR 1;2;Paz GONZLEZ 1;2;Xosé M.DOPAZO 1;2;Britt MELLSTROM 1;2 & José R.NARANJO 1;2 1 Department of Molecular and Cellular Biology;National Center of Biotechnology;Consejo Superior Investigaciones Cientificas;Madrid 28049;Spain;2Centro Investigacion Biomedica En Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnologia;Madrid 28049;Spain

..............page:786-792

STIM1 and Orai1:novel targets for vascular diseases?
Wei ZHANG & Mohamed TREBAK Center for Cardiovascular Sciences;Albany Medical College;Albany NY 12208;USA

..............page:780-785

Ca~(2+) signalling in cardiovascular disease:the role of the plasma membrane calcium pumps
Elizabeth J.CARTWRIGHT ;Delvac OCEANDY;Clare AUSTIN & Ludwig NEYSES Cardiovascular Medicine Research Group;Manchester Academic Health Science Centre;University of Manchester;Manchester M13 9PT;UK

..............page:691-698

Ca~(2+):a versatile master key for intracellular signaling cascades
Shi-Qiang WANG 1;Michael X ZHU 2 &Ernesto CARAFOLI 3 1State Key Lab of Biomembrane and Membrane Biotechnology;Peking University College of Life Sciences;Beijing 100871;China;2 Department of Integrative Biology and Pharmacology;the University of Texas Health Science Center at Houston;Houston 77030;USA;3Venetian Institute of Molecular Medicine;University of Padova;Padova 35121;Italy

..............page:683-685

Instructions for Authors

..............page:793-795

The structural biology of ryanodine receptors
Lynn KIMLICKA & Filip VAN PETEGEM University of British Columbia;Department of Biochemistry and Molecular Biology;Vancouver V6T 1Z3;Canada

..............page:712-724

Distinctive characteristics and functions of multiple mitochondrial Ca~(2+) influx mechanisms
Shi PAN 1;Shin-Young RYU 2 & Shey-Shing SHEU 1 1Center for Translational Medicine;Department of Medicine;Thomas Jefferson University;Philadelphia PA 19107;USA;2Department of Physiology;Seoul National University College of Medicine;Seoul 110-799;Republic of Korea

..............page:763-769

Structure and function of ALG-2,a penta-EF-hand calcium-dependent adaptor protein
Masatoshi MAKI 1;Hironori SUZUKI 1;2 & Hideki SHIBATA 1 1Department of Applied Molecular Biosciences;Graduate School of Bioagricultural Sciences;Nagoya University;Nagoya 464-8601;Japan;2Structural Biology Research Center;Photon Factory;Institute of Materials Structure Science;High Energy Accelerator Research Organization;Ibaraki 305-0801;Japan

..............page:770-779

The plasma membrane calcium pump in the hearing process:physiology and pathology
Ernesto CARAFOLI Venetian Institute of Molecular Medicine;University of Padova;Padova 35121;Italy

..............page:686-690